Dr. Ananthakumar Thillainathan

Community-acquired pneumonia (CAP) is a common cause of death and disability among people living with HIV. CAP is a major public health problem worldwide and has a high mortality rate. The treatment of CAP depends on the type of pneumonia and the cause. For example, bacterial pneumonia requires antibiotics to treat the infection. Antimicrobial therapy is a key component of treatment for community-acquired pneumonia. It involves the use of empirically selected antibiotics that are rapidly started to reduce symptoms, minimize the duration of hospitalization, and prevent complications. The main goals of antibiotic treatment are to identify the pathogen and kill it. The decision to start antimicrobial therapy depends on the type of infection and its severity, as well as the pattern of local antibiotic resistance and other patient-specific factors. The most common pathogens in community-acquired pneumonia are Streptococcus pneumoniae, Haemophilus influenzae, and atypical bacteria such ...

Alimentary Pharmacology & Therapeutics is an international journal . It publishes original research and reviews covering the gastrointestinal and hepato-biliary systems. It also covers epidemiology, drug safety, clinical trials, and meta-analyses. This journal is published by Wiley-Blackwell Publishing Ltd, UK. It is indexed in Scopus. Its year-wise impact score is 186. Alimentary Pharmacology & Therapeutics is an international journal concerned with the effects of drugs on the human gastrointestinal and hepato-biliary systems. The journal accepts original papers, systematic reviews, meta-analyses and randomised controlled trials. AP&T is particularly interested in the translation of research from bench to bedside and in the identification of novel therapeutic targets. The publisher of this journal is Wiley-Blackwell Publishing Ltd, which is located in United Kingdom. The ISSN of this journal is 02692813, 13652036. The IS0 4 standard abbreviation of this journal is 'Ali...

Infections at the incision site after surgery are a major risk after surgery. These can lead to further time spent in the hospital, additional surgeries, the temporary removal of prostheses, and additional rounds of antibiotics. Total hip arthroplasty (THA) and total knee arthroplasty (TKA) were compared for the number of surgical site infections (SSIs) they caused (TKA). The factors that raise the likelihood of SSIs were also evaluated. There is a wide range in the prevalence of SSIs, which are among the most common types of HAIs. Prophylactic antibiotic use during surgery, decreased frequency of repeat procedures, and improved sanitary conditions have all been implemented to reduce their occurrence. Yet, even in low and middle-income countries (LMICs) [1,2], SSI rates remain high. We conducted a retrospective case-control research at two institutions affiliated with tertiary hospitals to examine the temporal patterns of deep surgical site infections (SSIs) following six orthopedic s...

A new study found that a freeze-all strategy, which involves elective freezing all embryos, does not result in a higher chance of pregnancy than fresh embryo transfer . This suggests that a freeze-all strategy should be avoided for all women undergoing assisted reproductive technology treatment. While frozen embryo transfer (FET) has become a common option in reproductive medicine, the effectiveness of FET for improving pregnancy rates remains controversial. This study sought to fill the evidence gap by comparing the outcomes of frozen and fresh embryo transfers in ovulatory women. Infertility treatments such as in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) have become increasingly popular over the last decade. They have been shown to be successful in many cases, although they are not always a sure-fire way to get pregnant. During the transfer, a catheter-like tube is passed through the woman's cervix and into her uterus to transport the embryo. This is d...

Leprosy is a bacterial infection caused by Mycobacterium lipomatosis. It is a potentially lethal infectious disease. The most prevalent leprosy symptoms are painful blisters and sores on the hands, feet, and entire body. The bacteria Mycobacterium lipomatosis causes leprosy, a chronic infectious disease. It creates lumps and sores on the skin. In addition to these symptoms, it can cause damage to other sections of the body. Other symptoms include kidney, joint, and lymph node inflammation. They can also have an effect on the eyes The skin is the major site of infection for leprosy. The infection can cause nerve damage as it advances. This can result in numbness, weakness, and deformity. Symptoms can appear five to seven years after first coming into contact with an infected person. People who get leprosy are frequently in close, long-term contact with sick people. If you find yourself in this circumstance, seek assistance as soon as possible. Treatment can prevent the disease from spr...

Despite the complexity of both the gut microbiota and mood disorders , numerous studies have found a clear correlation between depressive symptoms and gut microbiome changes. This article investigates how the microbiome may be utilized to treat depression and illustrates some of these relationships. Our mental health depends on the composition of our gut flora. Depression has been linked to altered gut microbiome in animal studies. Uncertainty surrounds the function of the human gut microbiome, though. Stress and unbalanced diets may also have an impact on the gut microbiota's makeup. It has been demonstrated that alterations in the microbiota are the cause of stress-induced depressive-like behaviour in mice. Intervention with probiotics can lessen this habit. Folic acid has also been discovered to lessen depressive-like behavior. Depression is known to occur as a result of early stress and inflammation. The gut barrier may be damaged as a result of immunological and endocrine syst...